Nitric oxide in uremia: Effects of several potentially toxic guanidino compounds
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چکیده
منابع مشابه
Aloe vera toxic effects: expression of inducible nitric oxide synthase (iNOS) in testis of Wistar rat
Objective(s): Nitric oxide (NO), a product of inducible nitric oxide synthase (iNOS), contributes in germ cell apoptosis. This study was aimed to evaluate the effects of Aloe vera gel (AVG) on male Wistar rat reproductive organ, serum NO level, and expression of iNOS gene in leydig cells. Materials and Methods:Adult male Wistar rats (n=36) were used for experiments in three groups. The experim...
متن کاملGuanidino compounds in hyperargininemia.
Plasma and cerebrospinal fluid (CSF) concentrations and urinary excretion of guanidino compounds were investigated in a patient with hyperargininemia during the treatment with low-protein diet, oral administration of an essential amino acid mixture and sodium benzoate, or enzyme replacement therapy such as exchange transfusion or erythrocyte transfusion. In the patient, alpha-keto-delta-guanidi...
متن کاملaloe vera toxic effects: expression of inducible nitric oxide synthase (inos) in testis of wistar rat
objective(s): nitric oxide (no), a product of inducible nitric oxide synthase (inos), contributes in germ cell apoptosis. this study was aimed to evaluate the effects of aloe vera gel (avg) on male wistar rat reproductive organ, serum no level, and expression of inos gene in leydig cells. materials and methods:adult male wistar rats (n=36) were used for experiments in three groups. the experime...
متن کاملNitric oxide mediated the effects of nebivolol in cardiorenal syndrome
Objective(s): Despite several proposed mechanisms for the pathophysiology of cardiorenal syndrome (CRS), the exact mechanism remains unclear. Nitrosative stress has been argued as a key mechanism recently. Nebivolol is a beta-blocker with nitric oxide (NO)-releasing effect. In the present study, NO-mediated effects of two different treatment regimes of nebivolol in CRS...
متن کاملEffects of some guanidino compounds on human cerebral arteries.
BACKGROUND AND PURPOSE Accumulation of endogenous guanidino-substituted analogues of L-arginine in chronic renal failure might contribute to some of the vascular and neurological disorders of this pathology. We tested the hypothesis that in human cerebral arteries, some guanidino compounds may increase vascular tone, through nitric oxide (NO) synthase inhibition, and impair endothelium-dependen...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2003
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.63.s84.9.x